منابع مشابه
Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases.
Metastasis is the deadliest phase of cancer progression. Experimental models using immunodeficient mice have been used to gain insights into the mechanisms of metastasis. We report here the identification of a "metastasis aggressiveness gene expression signature" derived using human melanoma cells selected based on their metastatic potentials in a xenotransplant metastasis model. Comparison wit...
متن کاملZOSTERIFORM METASTASES IN A MAN WITH MALIGNANT MELANOMA
Zosteriform metastasis is a rare clinical distribution from spreading neoplasms of every organ to the skin. Tumors most often arise from a n internal o r hematologic malignancy. W e report a 69-year-old man, a known case of malignant melanoma of the left heel. In this case, multiple red-brown metastatic nodules appeared four months after diagnosis. Distribution of metastatic lesions resemb...
متن کاملcardiac metastases of malignant melanoma
malignant melanoma has the heart metastasis rate of 50 - 71%, which seems to be the highest among other malignancies. when a patient presents with cardiac metastases of melanoma, the disease has already spread through the body and therefore hardly curable. this brief review tried to introduce this important condition and discuss its frequency, presentation, diagnosis, histologic findings and tr...
متن کاملStandardized Cannabis sativa extract attenuates tau and stathmin gene expression in the melanoma cell line
Objective(s): Metastasis is the main cause of death in patients with melanoma. Cannabis-based medicines are effective adjunctive drugs in cancer patients. Tau and Stathmin proteins are the key proteins in cancer metastasis. Here we have investigated the effect of a standardized Cannabis sativa extract on cell migration and Tau and Stathmin gene expression in the melanoma cell line. Materials an...
متن کاملGene Expression Profiling for Melanoma
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1996
ISSN: 0022-202X
DOI: 10.1111/1523-1747.ep12343191